The Enrichment Center is required to remind you that the Weighted Companion Cube cannot talk. In the event that it does talk The Enrichment Centre asks you to ignore its advice.

There was even going to be a party for you. A big party that all your friends were invited to. I invited your best friend, the Companion Cube. Of course, he couldn't come because you murdered him. All your other friends couldn't come, either, because you don't have any other friends because of how unlikable you are. It says so right here in your personnel file: "Unlikable. Liked by no one. A bitter, unlikable loner, whose passing shall not be mourned. Shall NOT be mourned." That's exactly what it says. Very formal. Very official. It also says you were adopted, so that's funny, too.

Did you know you can donate one or all of your vital organs to the Aperture Science Self Esteem Fund for Girls? It's true!

GLaDOS: "Look, you're wasting your time. And, believe me, you don't have a whole lot left to waste. What's your point, anyway? Survival? Well, then, the last thing you want to do is hurt me. I have your brain scanned and permanently backed-up in case something terrible happens to you, which it's just about to. Don't believe me? Here, I'll put you on:"
Strange voice: Hellooooooooo!
GLaDOS: "That's you! That's how dumb you sound! You've been wrong about every single thing you've ever done, including this thing. You're not smart. You're not a scientist. You're not a doctor. You're not even a full-time employee! Where did your life go so wrong?"

The Enrichment Center reminds you that the Weighted Companion Cube will never threaten to stab you and, in fact, cannot speak.